NUTRITIONAL AND PHYTOCHEMICAL PROFILE OF A TRADITIONAL BEVERAGE MADE FROM ROASTED ROSELLE (HIBISCUS SABDARIFFA) SEEDS

Nutritional and phytochemical profile of a traditional beverage made from roasted roselle (Hibiscus sabdariffa) seeds

Abstract The consumption of locally available and affordable food with high nutritional properties is a recommended Vitamin B-12 solution to prevalent undernutrition in low-income countries.The objective of this study was to investigate the nutritional and phytochemical profile of a traditional beverage made from roasted green or red roselle seeds.

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Identifying opportunities for late-stage C-H alkylation with high-throughput experimentation and in silico reaction screening

Abstract Enhancing the properties of advanced drug candidates is aided by the direct incorporation of specific chemical groups, avoiding the need to construct the entire compound from the ground up.Nevertheless, their chemical intricacy often poses challenges in predicting reactivity for C-H activation reactions and planning their synthesis.We adop

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Repeated oxytocin prevents central sensitization by regulating synaptic plasticity via oxytocin receptor in a chronic migraine mouse model

Abstract Background Central sensitization is one of the characters of chronic migraine (CM).Aberrant synaptic plasticity can induce central sensitization.Oxytocin (OT), which is a hypothalamic hormone, plays an important antinociceptive role.However, the antinociceptive effect of OT and the underlying mechanism in CM remains Left Footplate unclear.

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